Factors influencing the migration result

The preparation of a compliant packaging is influenced by various factors such as the selection of appropriate cleaning agents, printing inks and varnishes, substrate and other printed aids. Since migration is not only reduced to the primary packaging, secondary packaging must also be considered in the migration analysis. Thus, self-adhesive labels are an integral part of the packaging, which must be fully involved in the migration analysis. Mainly small (<1000 da) and less complex molecules tend to migrate.

Typical materials with migration potential are: